List of hotels and motels in Brewton, Alabama. Brewton is a city in Escambia County, Alabama, United States. The city is the county seat of Escambia County with just a few hotels and motels. Brewton is located in south central Alabama, just north of the Florida Panhandle. ZIP codes: 36426-36427. Population: more than 5000 citizens. Find best hotels/motels and best deals near you or call to local travel agencies in Brewton.